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Abstract
Two new troponoides (1–2) were isolated from a 95% ethanol extract of the stems of Juniperus formosana (Cupressaceae), together with six known compounds (3–8). The structures of the new compounds were comprehensively characterized by high resolution electrospray ionization-mass spectrometry (HR-ESI-MS), 1D and 2D nuclear magnetic resonance (NMR). Compounds 1–7 were evaluated for their anti-inflammatory against the expression of IL-1β, IL-6 and TNF-α in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages. The new compounds showed moderate anti-inflammatory effect, while other compounds did show no activity.
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Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
The project was supported by Fujian Provincial Health Commission Project (2017FJZYZY105) and Fujian Province Young College Natural Science Foundation Key Project (No. JZ160399).