New and known phenylpropanoid glycosides from mountain cultivated ginseng

Abstract

Two new phenylpropanoid glycosides elucidated as 2,6-dimethoxyphenyl-4-propylene-1-O-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside (1) and 2-methoxyphenyl-4-propylene-1-O-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside (2), along with three known phenylpropanoid glycosides (3–5) were isolated from Mountain Cultivated Ginseng. The structures of compounds 1–5 were elucidated on the basis of comprehensive spectroscopic data including 1D, 2D NMR spectra, and MS. In addition, in vitro cytotoxicity of all the isolated compounds was evaluated against HELA cell.

Graphical Abstract

Keywords:

• Panax ginseng C.A. Meyer
• mountain cultivated ginseng
• phenylpropanoid glycoside
• cytotoxicity

Disclosure statement

The authors declare no conflicts of interest.

Additional information

Funding

This work was supported by the National Key R&D Program of China under Grant (2017YFC1702302); Liaoning Revitalization Talents Program under Grant (XLYC1902119); Liaoning Programs for Science and Technology Development under Grant (2017226009); and The Fourth National Survey on Chinese Materia Medica Resources in Liaoning Province under Grant (2018018).