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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 3
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Research Articles

Stilbenoids from the roots of Stemona tuberosa

Hong-Mei Lia School of Biological Science and Technology, University of Jinan, Jinan, ChinaView further author information
,
Tian-Tian Hea School of Biological Science and Technology, University of Jinan, Jinan, ChinaView further author information
,
Miao Zhanga School of Biological Science and Technology, University of Jinan, Jinan, ChinaView further author information
,
Jia-Ning Liua School of Biological Science and Technology, University of Jinan, Jinan, ChinaView further author information
,
Xue Zhaoa School of Biological Science and Technology, University of Jinan, Jinan, ChinaView further author information
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Jie Liub Shandong Provincial Engineering Research Center for Medicines of Orthopedic Pain, Shandong Mingren Freda Pharmaceutical Co., Ltd, Jinan, ChinaCorrespondence[email protected] [email protected]
View further author information
&
Lei Fanga School of Biological Science and Technology, University of Jinan, Jinan, ChinaORCID Iconhttps://orcid.org/0000-0003-3999-7170View further author information
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Pages 695-700 | Received 19 Apr 2020, Accepted 06 Jul 2020, Published online: 27 Jul 2020
 
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Abstract

Two new stilbenoids, stemobenoids A (1) and B (2), together with three known compounds were obtained from the roots of Stemona tuberosa. The structures of the new compounds were established by extensive spectroscopic analysis, including HRMS, 1D and 2D NMR data. Compounds 1 and 2 displayed potent quinone reductase inducing activity in Hepa 1c1c7 cells.

Graphical Abstract

Disclosure statement

The authors declare that there are no conflicts of interest.

Additional information

Funding

This work was supported by Postdoctoral Science Foundation of China (2017M622268), and the National Key Research and Development Project (2017YFC1702702, 2017YFC1700705).

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