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Abstract
A new polyacetylene glucoside, Dendranacetylene A (1), and a known compound 8E-decaene-4,6-diyn-1-O-β-d-glucopyranosyl-(1ʺ→2ʺ)-β-d-glucopyranoside (2) were isolated from the flowers of Dendranthema morifolium (Ramat.) kitam. The chemical structures of these compounds were elucidated by NMR and HR-ESI-MS analysis, and comparing these results with data reported in literatures. Additionally, the anti-inflammatory effects of compounds 1 and 2 were evaluated on RAW264.7 murine macrophage cells induced by lipopolysaccharide (LPS). The two compounds significantly inhibited the NO production in LPS-induced RAW 264.7 murine macrophage cells and exhibited anti-inflammatory effects.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
Our work was supported by the Central Government Guide Local Science and Technology Development Funds (14104349), the Key Scientific Research Project of Institutions of Higher Learning in Henan (21B360003), the Special Project of Scientific Research on Traditional Chinese Medicine in Henan (20-21ZY2151) and the Doctoral Research Fund of Henan University of Chinese Medicine (BSJJ2018-08).