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Abstract
A undescribed phenolic glycoside, trochinenol A (1), was isolated from the flowers of Trollius chinensis Bunge and the structure was identified by spectroscopic methods. Its anti-inflammatory and antibacterial effects were investigated by broth microdilution and NF-κB reporter gene assays. Consequently, compound 1 exhibited an appreciable effect against Staphylococcus aureus with the MIC value of 6.25 µg/mL. Besides, it showed moderate effect against TNFα-induced activation of NF-κB pathway.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Figure 1. Structure of compound 1 isolated from Trollius chinensis Bunge.
Additional information
Funding
This project was financially supported by grants from Fundamental Research Funds for the Central Universities (No. 20720190079), and Natural Science Foundation of Fujian Province of China (No. 2019J007).