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Abstract
A new isoflavone (Z)-5,7,4′-trihydroxy-3′-[3-hydroxy-3-methyl-1-butenyl] isoflavone (1) together with seven known isoflavones (2–8) were isolated from the fruits of the Ficus auriculata. Their structures were established on the basis of 1 D, 2 D-NMR spectroscopic data and HR-ESI-MS analysis. All compounds were evaluated for their antibacterial activities against five pathogenic bacteria in vitro. Compounds 3 and 4 exhibited significant antibacterial activities against five pathogenic bacteria with the MIC values ranging from 1.25 to 20 μg/mL.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was supported by the the National natural sciences foundation of China (Nos. 8,136,047,821,362,009), the open foundation of Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province (rdzw2020s02) Basic Ability of Scientific Research Improvement Project on the Young and Middle-aged Teachers in the Colleges and Universitites in Guangxi (No. 2020KY14011); Scientific Research Fund for High Level Talents of Yulin Normal University (No. G2019ZK21); Scientific Research Project of Yulin Normal University (No. 2019YJKY17).