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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 15
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Research Articles

Two new phenolic compounds from the lichen Parmotrema cristiferum growing in Vietnam

Nguyen-Kim-Tuyen Phama Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City, VietnamView further author information
,
Huy Truong Nguyenb Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, VietnamView further author information
,
Thi-Bich-Ngoc Daoc Department of Chemistry, University of Education, Ho Chi Minh City, VietnamView further author information
,
Kim Long Vu-Huynhb Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, VietnamView further author information
,
Thi-Quynh-Trang Nguyena Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City, VietnamView further author information
,
Bui-Linh-Chi Huynhd Department of Nature, Dong Nai University, Dong Nai province, VietnamView further author information
,
Tien-Dung Lee Vietnam Academy of Science and Technology, Graduate University of Science and Technology, Ha Noi, Vietnam;f Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City, VietnamView further author information
,
Ngoc-Hung Nguyenc Department of Chemistry, University of Education, Ho Chi Minh City, VietnamView further author information
,
Ngoc-Hong Nguyeng CirTech Institute, Ho Chi Minh City University of Technology (HUTECH), Ho Chi Minh City, VietnamCorrespondence[email protected] [email protected]
View further author information
&
Thuc-Huy Duongc Department of Chemistry, University of Education, Ho Chi Minh City, VietnamCorrespondence[email protected] [email protected]
View further author information
 show all
Pages 3865-3871 | Received 25 Dec 2020, Accepted 15 Feb 2021, Published online: 03 Mar 2021
 
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Abstract

Two new phenolic compounds, cristiferides A-B (1-2) together with six known compounds, 2,4-dihydroxyphthalide (3), lecanoric acid (4), orsellinic acid (5), 5-chloroorsellinic acid (6), methyl haematommate (7), and methyl β-orsellinate (8) were isolated from the lichen Parmotrema cristiferum (Taylor) Hale (Parmeliaceae). The structures of isolated compounds were identified from its spectroscopic data and by comparison with the literatures. Compounds 1-3 and 6-8 were evaluated for alpha-glucosidase inhibition. Compounds 2 and 7 revealed potent activity with IC50 values of 72.66 μM and 48.73 μM, respectively.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research is funded by Saigon University under grant number TĐ 2020-53.

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