Chemical constituents from Lactuca plumieri (L.) Gren. & Godr. (Asteraceae)

Abstract

This is the first report concerning the natural products of the hitherto unstudied Lactuca plumieri (L.) Gren. & Godr., a member of the tribe Cichorieae (Asteraceae). From aerial parts and roots of this plant, five sesquiterpene lactones and one coumarin were isolated. The compounds were identified as sonchuside A, 11β,13-dihydrolactucin-8-O-acetate, 11β,13-dihydrolactucin, cichorioside B, 11β,13-dihydrolactucin-8-O-acetate-15-O-β-glucopyranoside and coumarin – cichoriin. Their structures were established by ¹H NMR. Moreover, HPLC/PAD analysis of a hydroalcoholic extract from the aerial parts of the plant revealed the presence of caffeic acid derivatives, coumarins and flavonoids commonly found in lettuces.

Keywords:

• Asteraceae
• Lactuca plumieri
• sesquiterpenoids
• coumarin
• caffeic acid derivatives

Acknowledgements

The financial support of the Ministry of Science and Higher Education, Poland, (statutory activity founding) is gratefully acknowledged.

Disclosure statement

No potential conflict of interest was reported by the authors.