A new dimethoxy dihydrochalcone isolated from the shoots of Empetrum nigrum L.

Abstract

A new dihydrochalcone, 2',4'-dimethoxydihydrochalcone (1), together with 7 known compounds, 2',4'-dihydroxydihydrochalcone (2), 2'-hydroxy-4'-methoxydihydrochalcone (3), 2'-hydroxy-4'-methoxychalcone (4), 1-(3,5-dihydroxy-4-methoxyphenyl)-2-(3-hydroxyphenyl) ethane (5), 2,3,4,7-tetramethoxy-9,10-dihydrophenanthrene (6), 5-hydroxy-2,3,4-trimethoxy-9,10-dihydrophenanthrene (7) and 5,7-dihydroxy-6,8-dimethyl flavanone (8) were isolated from the shoots of Empetrum nigrum L. The structures of these compounds were elucidated using 1D and 2D NMR experiments along with HR-ESI-MS. Compound 6 is reported for the genus Empetrum for the first time.

Keywords:

• Empetrum nigrum
• black crowberry
• dihydrochalcone
• bibenzyl
• dihydrophenanthrene
• flavanone
• secondary metabolites

Acknowledgements

The isolation and structural elucidation of all compounds was performed at the Department of Pharmacognosy, SPCPU. HR-ESI-MS and NMR data was obtained using equipment from the Center for Chemical Analysis and Materials Research, Magnetic Resonance Research Centre of the Research Park of the Saint Petersburg State University.

Disclosure statement

No potential conflict of interest was reported by the authors.