Berectones A and B: Two new rotenoids from the aerial parts of Boerhavia erecta

Abstract

Two previously unreported rotenoids, berectones A and B (1 and 2), along with four known compounds, 3,3′,4′-tri-O-methylellagic acid (3), kaempferol (4), 7,4′-dihydroxy-8-methoxyisoflavone (5), and trans-N-caffeoyltyramine (6) were isolated from the aerial parts of Boerhavia erecta. The structures of all isolated compounds were fully characterized using spectroscopic data, as well as comparison with the previous literature. Compound 6 exhibited the strongest inhibitory activity toward α-glucosidase with IC₅₀ value of 4.74 µM.

Keywords:

• Nyctaginaceae
• Boerhavia erecta
• berectones A and B
• rotenoid
• α-glucosidase inhibition

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Research equipments and chemicals were supported by Thammasat University Research Unit in Natural Products Chemistry and Bioactivities.