A comprehensive insight on the biological potential of embelin and its derivatives

Abstract

Naturally occurring bioactive molecules are known for their diverse biological applications such as antimicrobial, anticancer, anti-inflammatory, and analgesic activities. Also, some of the natural products act as medicinal drugs. Further, bioactive cell-permeable molecule embelin has been reported for its diverse biological activities such as antimalarial, anticancer, and anti-inflammatory in the literature. With the continuation of our research work on biologically active molecules, based on structural activity relationship and docking studies of embelin and its derivatives, we have reported target-specific anticancer and antimalarial activities of embelin and its analogs. Also, it has been reported in many recent research articles that embelin and its derivatives are known to possess medicinal properties. This review mainly highlights recent reports on broad-spectrum biological activities of the embelin and its analogs to date.

Graphical Abstract

Keywords:

• Embelin
• anticancer
• antimalarial
• antimicrobial
• anti-diabetic
• antiviral
• antioxidant activity

Acknowledgments

The authors are thankful to Dr. K.Shymsunder, HOD Chemistry, IADC-A, for his constant encouragement. The authors acknowledge the management of the college for providing the necessary facility for the completion of this review article.

Disclosure statement

No potential conflict of interest was reported by the authors.