Abstract
Three new biflavonoids, umcephabiovins C − E (1 − 3), along with fourteen known compounds were isolated from the twigs and leaves of Cephalotaxus oliveri. Their structures and configurations were elucidated by UV, IR, NMR, ECD, and HR-ESI-MS spectra. Compounds 1 − 3 exhibited significant α-glucosidase inhibitory activity with IC50 values of 7.05 ± 2.66, 24.45 ± 4.73, and 1.84 ± 1.14 μM, respectively. Compound 11 showed moderate cytotoxicity against the BaF3/T315I cell line.
Graphical Abstract
![](/cms/asset/dae8c1fe-96c9-475a-8051-da3b0a7d8b78/gnpl_a_1958328_uf0001_c.jpg)
Disclosure statement
All the authors have no conflict of interest to declare.