Abstract
Phytochemical investigation the resins of Ferula sinkiangensis K.M.Shen yielded three new tetrahydrobenzofuran derivatives named as Sinkiangensis A-C (1–3). The structures of the new compounds were elucidated by analysis of their NMR, HRMS, and ECD spectra, and the absolute configurations were established through the comparison of experimental and calculated ECD spectra. Compound 3 exhibited moderate antitumor activities against AGS cancer cell with IC50 values of 15.6 µM. Moreover, assays demonstrated that compound 3 could induce AGS cancer cell apoptosis.
Graphical abstract
Disclosure statement
No potential conflict of interest was reported by the authors.