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Natural Product Research
Formerly Natural Product Letters
Volume 37, 2023 - Issue 17
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Short communications

LC-MS profile, in vitro acetylcholinesterase inhibitory, antibacterial and hemostatic properties of Ranunculus bullatus extract

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Pages 2911-2915 | Received 19 Jul 2022, Accepted 07 Oct 2022, Published online: 20 Oct 2022
 

Abstract

The ethanol extract from aerial parts of Ranunculus were investigated for its chemical composition by LC-ESI-MS/MS technique, which allowed to identify a series of glycosylated flavonoids and one phenolic acid. RBEE extract showed acetyl-cholinesterase inhibition higher than the reference compound Galantamine at a concentrationof 200 µg/mL. A moderate antibacterial activity of the extract was also obtained against Staphylococcus aureus ATCC43300, Citrobacter freundii ATCC8090, and Proteus vulgaris ATCC29905 at a concentration 100 µg. Additionally, a good reduction in plasma coagulation time at 200 μL was also observed for RBEE.

Graphical Abstract

Acknowledgment

The authors express their thanks to the team of ‘Laboratory of Bioorganic Chemistry, university of Trento (Italy)’ for recording LC-ESI-MS spectra.

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding

The author(s) reported there is no funding associated with the work featured in this article.

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

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