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Abstract
Two new monoterpene esters, illigerates H and I (1 and 2), and six known compounds actinodaphine (3), bulbocupnine (4), stephanine (5), hypserpanine B (6), betulinic acid (7) and gallic acid (8) were obtained from the root of Illigera paviflora Dunn. Their structures were elucidated by spectroscopic analysis. Anti-inflammatory and α-glucosidase inhibitory activity of some isolated compounds were assessed. Two monoterpenes 1 and 2 exhibited weak in vitro anti-inflammatory activity (IC50 64.5 ± 5.3 and 79.2 ± 7.5 μM) while compounds 3–6 showed inhibition of α-glucosidase with IC50 values ranged from 87.17 to 118.74 μM.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by a grant from the National Natural Science Foundation of China (No. 81903519, 81960783), the Major Scientific and Technological Special Project of Yunnan Province (202102AA100018) and Foundation of Key Laboratory of Chemistry in Ethnic Medicinal Resources, Yunnan Minzu University (2019MZY19, MY20210505).