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Abstract
Phytochemical study of the Salvia santolinifolia root extract resulted in the isolation of one new quinone diterpenoid, aegyptinone E (1) as well as two known ones, aegyptinone A (2) and aegyptinone D (3). All the isolated compounds were reported for the first time from S. santolinifolia. Spectroscopic analyses including 1 D and 2 D NMR and HRESIMS were used to determine the chemical structures. Aegyptinone A (2) showed moderate antibacterial activity against Staphylococcus aureus, Staphylococcus epidermis, and Bacillus subtilis with MIC of 25 μg/mL.
GRAPHICAL ABSTRACT
Disclosure statement
The authors declare no conflict of interest.
Research involving human participants and/or animals
This article does not contain any studies with human participants and/or animals performed by any of the authors.
Additional information
Funding
This research was supported by the Mashhad University of Medical Sciences (970763) Research Council.