https://orcid.org/0000-0003-3999-7170
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Abstract
Two new monoterpenoid indole alkaloids, named taberibogines E and F (1 and 2), together with three known ones (3–5) were isolated from the stems of Tabernaemontana bovina Lour (Apocynaceae). Their structures including absolute configurations were elucidated from a combination of NMR and HRESIMS data and NMR calculations as well as DP4+ probability analyses. Compounds 1 and 2 exhibited inhibitory effects on LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages.
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Disclosure statement
The authors declare that there are no conflicts of interest.
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Funding
This work was financially supported by Natural Science Foundation of China (22077049), Shandong Provincial Technological Innovation and Guidance Project (2017YFC1702702), the Higher Educational Science and Technology Program of Jinan City (2020GXRC060) and Science and Technology Program of University of Jinan (XKY2017).