Abstract
Polyphenols, the important secondary metabolites, consist of multiple phytochemicals and show numerous physiological effects. Flavones play a significant role in various chronic disorders such as diabetes.. In this study, all the flavones were encountered, and it was further filtered based on their drug-likeness properties and pharmacokinetic parameters. Existing literature confirms that flavone-based compounds are suitable as the drug of choice in sarcopenic obesity. A molecular docking study was performed toward the myostatin inhibition profile of the flavones using PDB:3HH2 as a target site. This computer-aided drug design helps select lead molecules in novel drug discovery.
Acknowledgement
We would like to thank SRMIST for providing technical-oriented sources.
Author contributions
Sarvesh Sabarathinam: designed the research and carried out the experiment and Sanjana Satheesh and Arun Raja: analyzed the data. All authors read and approved the final manuscript.
Disclosure statement
No potential conflict of interest was reported by the authors.