Phytochemical characterization and antifungal potential of leaf extracts of Mosiera bullata

Abstract

The investigation of natural alternatives to conventional fungicides is of imminent need. Mosiera bullata (Britton & P. Wilson) Bisse is a Cuban endemic plant species belonging to the Myrtaceae family. The objective of the present study was to perform a bioassay-guided fractionation to explore the potential of extracts and fractions from M. bullata leaves against a panel of fungal plant pathogens. The M. bullata total extract was confirmed to have good antifungal activity against R. oryzae (IC₅₀ = 4.86 µg/mL) and moderate activity against F. oxysporum (IC₅₀ = 352.40 µg/mL) and F. solani (IC₅₀ = 427.38 µg/mL) and fungicidal effect against R. oryzae. Five compounds belonging to the class of phloroglucinol dimers were tentatively characterized by UHPLC-HRMS and reported for the first time in M. bullata and the genus Mosiera. These results suggest the potential of M. bullata total extract as a natural antifungal product for the control of diseases in agriculture.

Graphical Abstract

Keywords:

• Natural products
• biofungicide
• phloroglucinol dimers

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This research was supported by VLIR-TEAM, grant number CU2017TEA433A102 coordinated by Paul Cos, Luc Pieters and Enrique Molina Pérez. This research was supported by the University of Antwerp, Belgium and Bioplantas Centre, University of Ciego de Ávila, Cuba. Authors are grateful to Pathy Kibungu, Nele Geerts, Anda Sipola, Natascha Van Pelt and Margot Desmet for their collaboration during this investigation.