Chemical composition and antimicrobial activity of essential oil from Popowia pisocarpa (Bl.) Endl., Walp. Repert. (Annonaceae)

Abstract

The volatile compositions and antimicrobial activity of aerial parts of Popowia pisocarpa from Vietnam were reported for the first time. From the GC/MS spectral, spathulenol (35.9%), bicyclogermacrene (5.7%) and muurola-4,10(14)-dien-1β-ol (4.2%) among the sesquiterpenoids, along with 4,4-dimethyl-3-(3-methylbut-3-enylidene)-2-methylenebicyclo[4,1,0]heptane (17.7%), an unsaturated cyclic compound, were the main constituents of the essential oil. Monoterpenoids were not identified in the essential oil. The essential oil displayed antimicrobial activity against the Gram-negative Escherichia coli ATCC 25922 with MIC value of 16.0 µg/mL and IC₅₀ value of 8.52 µg/mL. In addition, the essential oil also exhibited activity towards the Gram-positive bacteria of Staphylococcus aureus ATCC 13709, Bacillus subtilis ATCC 6633, and Lactobacillus fermentum N4 with MIC value of 64.0 µg/mL each and corresponding IC₅₀ values of 11.06 µg/mL, 26.47 µg/mL and 15.68 µg/mL, respectively. The essential oil did not inhibit the growth of Pseudomonas aeruginosa ATCC 15442, Salmonella enterica and the yeast Candida albicans ATCC 10231.

Graphical Abstract

Keywords:

• Popowia pisocarpa
• Annonaceae
• sesquiterpenes
• antimicrobial activity

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research was supported by Hue University (grant No. DHH2022-04-177) and Vingroup Innovation Foundation (Dien Dinh was supported by the Master’s and PhD Scholarship Programme of VINIF [code VINIF.2022.ThS.012]).