Abstract
Two new alkaloids designated aspernigrin E (1) and pyranonigrin L (2) were isolated from mangrove endophytic fungus Aspergillus fumigatus SAS10, together with the known alkaloid compounds pyranonigrin A (3), asperazine (4), (+)-iso-pestalazine A (5), pestalazine A (6), and pestalazine B (7). The planar structures of the new compounds were elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configurations of compounds 1 and 2 were determined by comparison of the electronic circular dichroic (ECD) spectra with the calculated ECD spectra. All these compounds were tested for anti-bacterial activity.
Graphical Abstract
![](/cms/asset/d1b4af80-8a04-4dd5-86e3-30ec669bfe2f/gnpl_a_2272289_uf0001_c.jpg)
Disclosure statement
No potential conflict of interest was reported by the author(s).