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Abstract
Sarcanoids A and B (1 and 2), two new lindenane-type sesquiterpenoid dimers with a γ-hydroxysenecioate moiety at C-15′, were isolated from the ethyl acetate extract of Sarcandra glabra. The structures were elucidated by extensive analysis of spectroscopic data, and their absolute configurations were determined by single-crystal X-ray crystallography. Compounds 1 and 2 showed moderate inhibitory activities on the nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW264.7 macrophages.
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Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This work was supported by the National Natural Science Foundation of China [grant number 82073735], the scientific and technological project of Yunfu [grant number 2021020605], Modern Seed Industry (Crop) Industrial Park Project of Huangpu [grant number GDSCYY2020-64], and the Yunnan Science and Technology Talents and Platform Program [grant number 202205AF150071].