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Abstract
Two new sulphur-containing amides, glylucidamides C–D (1–2), along with twelve known analogues (3–14) were isolated and characterised from the leaves of Glycosmis lucida. The chemical structures of 1 and 2 were elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons their data with those reported in the literatures. All new compounds were evaluated for their anti-inflammatory activities via examining the inhibitory activity on nitric oxide (NO) production induced by lipopolysaccharide in mouse macrophage RAW 264.7 cells in vitro.
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Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This research was financially supported by the Characteristic Innovation Project of University in Guangdong Province (2023KTSCX073), the Young Innovative Talents Project of General Colleges and Universities in Guangdong Province (No. 2021KQNCX049), the Special program for Natural Science Talents of Lingnan Normal University (Nos. ZL1903 and ZL1403), and the Open Project of Western Guangdong Characteristic Biology and Medicine Engineering and Research Centre (No. 2022-K04).