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Original Article

Auditory measures in clinically depressed individuals. I. Basic measures and transient otoacoustic emissions

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Pages 493-498 | Received 16 May 2003, Accepted 26 Nov 2003, Published online: 07 Jul 2009
 

Abstract

This is the first paper in a series of two papers addressing possible differences in auditory function between individuals with and without clinical depression. Clinical depression is a common yet serious medical condition diagnosed based on the patient's symptoms. Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed if the symptoms are determined to be consistent with low serotonin levels. Three groups of individuals were tested: the control group consisted of subjects with no depression; the medicated group consisted of subjects with depression who were on SSRIs for at least a month; the unmedicated group consisted of subjects with depression who were unmedicated for at least a month. The results indicated no significant differences between the groups in pure-tone threshold, uncomfortable loudness levels, dynamic range of hearing, and acoustic reflex thresholds. However, the unmedicated group exhibited higher amplitudes of transient otoacoustic emissions compared to the control group, especially in the right ear.

Sumario

Este es la primera en una serie de dos publicaciones que estudian posibles diferencias en la función auditiva entre individuos con y sin depresión clínica. La depresión clínica es una condición médica común y seria, cuyo diagnóstico se basa en los síntomas del paciente. Los inhibidores selectivos de la captación de serotonina (SSRI) se prescriben ampliamente, si se determina que los síntomas del paciente son consistentes con una serotonina baja. Se evaluaron a tres grupos de individuos: el grupo control se conformó con sujetos no deprimidos; el grupo con medicación involucró sujetos con depresión que habían tomado los SSRI por al menos un mes; el grupo sin medicación consistió de sujetos con depresión que no había recibido medicación durante el último mes.Los resultados no mostraron diferencias significativas entre los grupos tanto en los umbrales de tonos puros, enlos niveles no confortables de sonoridad, en el rango dinámico de la audición y en los umbrales de los reflejos acústicos. Sin embargo, el grupo sin medicación mostró amplitudes mayores en las emisiones otoacústicas evocadas por transitorios, especialmente en el oído derecho, al ser comparado con el grupo control.

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