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Original Article

Binaural interactions of electrically and acoustically evoked responses recorded from the inferior colliculus of guinea pigs

Interacciones binaurales de las respuestas evocadas acústica y eléctricamente obtenidas del colículo inferior de cobayos

, , , , &
Pages 309-320 | Received 02 Mar 2006, Published online: 07 Jul 2009
 

Abstract

Binaural interactions within the inferior colliculus (IC) elicited by electric and acoustic stimuli were investigated in this study. Using a guinea pig model, binaural acoustic stimuli were presented with different time delays, as were combinations of binaural electric and acoustic stimuli. Averaged evoked potentials were measured using electrodes inserted into the central nucleus of the IC to obtain the binaural interaction component (BIC), computed by subtracting the sum of the two monaural responses from the binaural response. The BICs to acoustic-acoustic stimulation and electric-acoustic stimulation were found to be similar. The BIC amplitude increased with stimulus intensity, but the shapes of the delay functions were similar across the levels tested. The gross-potential data are thus consistent with the thesis that the central auditory system processes binaural electric and acoustic stimuli in a similar manner. These results suggest that the binaural auditory system can process combinations of electric and acoustic stimulation presented across ears and that evoked gross potentials may be used to measure such interaction.

Acronyms
ABR=

Auditory brainstem response

IC=

Inferior colliculus

RMS=

Root-mean-square

BIC=

Binaural interaction component

Acronyms
ABR=

Auditory brainstem response

IC=

Inferior colliculus

RMS=

Root-mean-square

BIC=

Binaural interaction component

Sumario

En este estudio se investigaron las interacciones binaurales en el colículo inferior (IC) evocadas por estímulos eléctricos y acústicos. Utilizando a un cobayo, se le presentaron estímulos acústicos binaurales con diferentes retrasos temporales en combinaciones de estímulos acústicos y eléctricos binaurales. Se midieron los potenciales evocados por medio de electrodos insertados en el núcleo central del IC para obtener el componente de la interacción binaural (BIC), que se calculó al sustraer la suma de las dos respuestas monoaurales de la respuesta binaural. Se encontró que los BIC de la estimulación acústica-acústica y la eléctrica acústica fueron similares. La amplitud del BIC se incrementó con la intensidad del estímulo, pero las formas de las funciones del retraso fueron similares a través de los niveles examinados. Los datos gruesos de los potenciales son por tanto consistentes con la tesis de que el sistema auditivo central procesa estímulos acústicos y eléctricos en forma similar. Estos resultados sugieren que el sistema auditivo binaural puede procesar combinaciones de estimulación eléctrica y acústica presentada en ambos oídos y que los potenciales evocados gruesos pueden ser utilizados para medir tal interacción.

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