Automated detection of auditory response: applying sequential detection strategies with constant significance level to magnitude-squared coherence

Abstracts

Objective: The detection of the auditory steady-state responses is usually performed by an appropriate objective response detector applied to stimulus-related epochs of the raw electroencephalogram (EEG). In order to improve the detection time, sequential detection strategies are usually used. These multiple tests strategies increase the probability of mistakenly detecting a response. The aim of this study was to develop strategies to determine the critical values for the sequential detection strategies based on constant significance level tests.

Design: Extensive Monte Carlo simulations were used to test these strategies for the magnitude-squared coherence (MSC) detector. The performances of these strategies were compared with previous works found in the literature.

Study sample: All strategies were applied to synthetic and real EEG datasets.

Results: The strategies ensure the desired significance level at the end of the sequential detection strategy. The simulated results are in accordance with the real data results.

Conclusions: For the MSC detector, where the critical value depends on the number of epochs, the proposed sequential detection strategies obtain better performance regarding test time and detection rate, but worse overall detection rate compared to applying a test only once.

Keywords:

• auditory steady-state response
• magnitude-squared coherence
• multiple testing
• critical values

Acknowledgements

This work received financial support of the Brazilian Agencies: CNPq, FAPEMIG and CAPES.

Ethical approval

Work approved by the Local Ethics Committee. (UFV/CAAE: 56346916.4.0000.5153)

Disclosure statement

No potential conflict of interest was reported by the authors.