Abstract
The present article describes the synthesis of new 10H-phenothiazines using the Smiles rearrangement. These synthesized phenothiazines on oxidation with 30% hydrogen peroxide in glacial acetic acid yield sulfones, and when treated with sugar give ribofuranosides. These compounds are evaluated for their anthelmintic and antimicrobial activities. The structural assignment of the synthesized compounds is made on the basis of elemental analysis and spectroscopic data.
Acknowledgments
The authors are thankful to the Department of Chemistry, University of Rajasthan, Jaipur, for providing laboratory facilities and spectral data analysis. The authors are also thankful to Rajiv Academy for Pharmacy, Mathura, for assistance in carrying out the biological activities. UGC (Major Research Project) and UGC Research Award Scheme, UGC, New Delhi are duly acknowledged for financial support.