Abstract
cN-II is a cytosolic 5’-nucleotidase with preference for IMP and GMP over AMP. The enzyme has been extensively studied over the last 20-30 years both for its enzymatic activity, structure, role in nucleotide metabolism and in cell biology, as well as in diseases. With the aim of highlighting the complexity of the enzyme, I will, as during PP21, present work from our group and others working on cN-II and its various roles and not give an exhaustive overview of new data.
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Acknowledgements
LPJ receives funding from Olav Raagholt og Gerd Meidel Raagholts stiftelse for forskning.
Funding
The author(s) reported there is no funding associated with the work featured in this article.