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Articles

The amazing cN-II, the enzyme that keeps us busy

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Pages 239-246 | Received 27 Jul 2021, Accepted 17 Sep 2021, Published online: 06 Oct 2021
 

Abstract

cN-II is a cytosolic 5’-nucleotidase with preference for IMP and GMP over AMP. The enzyme has been extensively studied over the last 20-30 years both for its enzymatic activity, structure, role in nucleotide metabolism and in cell biology, as well as in diseases. With the aim of highlighting the complexity of the enzyme, I will, as during PP21, present work from our group and others working on cN-II and its various roles and not give an exhaustive overview of new data.

Acknowledgements

LPJ receives funding from Olav Raagholt og Gerd Meidel Raagholts stiftelse for forskning.

Funding

The author(s) reported there is no funding associated with the work featured in this article.

Additional information

Funding

LPJ receives funding from Olav Raagholt og Gerd Meidel Raagholts stiftelse for forskning.
This article is part of the following collections:
19th Biennial Symposium on Purine and Pyrimidine Metabolism (PP21)

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