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Abstract
Ischemic stroke (IS) is a global health challenge leading to life-long disabilities or the deaths of patients. IS is a complex disease where genetic and environmental factors are both concerned with the pathophysiology of the condition. Here, we aimed to investigate various microRNA (miRNA) expressions and their targets in IS. A rapid and accurate diagnosis of acute IS is important to perform appropriate treatment. Therefore, there is a need for a more rapid and simple tool to carry out an acute diagnosis of IS. miRNAs are small RNA molecules serving as precious biomarkers due to their easy detection and stability in blood samples. The present systematic review aimed to summarize previous studies investigating several miRNA expressions and their targets in IS.
Acknowledgment
The authors thank Numan Duran for language editing.
Authors’ contributions
Ummugulsum Can and Ebru Marzioglu were involved in the design and writing the review.
Disclosure statement
The authors have no conflict of interests to declare concerning the review. The authors have read the manuscript and have agreed to submit it in its current form for consideration to be published in the journal.
Funding
The author(s) reported there is no funding associated with the work featured in this article.