Abstract
Adenosine deaminase (ADA) and adenylate deaminase (AMPDA) catalyze the deamination of 2 ′,3 ′-O-isopropylideneadenosine-5′-carboxylic acid to the corresponding inosine derivative and dependence of the rate of enzymatic reaction on the ionization degree of the substrate has been studied at different pH values.
This work has been financially supported by Università degli Studi di Milano (Fondi FIRST).
Notes
a 20% conversion.
b 46% conversion.