Abstract
New 2-amino-6-oxo-8-thioxo-9-substituted purine derivatives were prepared and assayed for the in vitro cytotoxic activity. Some products exhibited moderate activity on HT-1080 cells and rather high activity on MG-22A cells.
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Notes
aTD50-Concentration (mole/l × 103) providing 50% cell killing effect [(CV+ MTT)/2]; NO Concentration (%).
bNA-inactive.