Abstract
The nucleoside analogues 2′-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments.
This research was funded by grants from BBSRC and EU. Oligonucleotide synthesis was carried out by ATDBio Ltd. (www.atdbio.com).