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Nucleosides, Nucleotides & Nucleic Acids Volume 26, 2007 - Issue 10-12
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Original Articles

Synthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an H-Phosphonate Approach

Hongyan Liu Department of Chemistry, Duke University, Durham, North Carolina, USA
,
Syed N. Hashmi Department of Chemistry, Duke University, Durham, North Carolina, USA
&
Barbara Ramsay Shaw Department of Chemistry, Duke University, Durham, North Carolina, USA
Pages 1455-1457 | Published online: 05 Dec 2007
 
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Abstract

9-Fluorenemethyl boranophosphonate 6 and its boranophosphonodiphosphate 7 were synthesized via an H-phosphonate approach. The method is efficient for the synthesis of acyclic compounds 6 & 7 , and can be explored for the synthesis of nucleoside 5′-deoxy boranophosphonodiphosphate.

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