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Original Articles

Novel Fluorophores for Labeling of Nucleosides and Oligonucleotides

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Pages 1573-1576 | Published online: 05 Dec 2007
 

Abstract

Five novel fluorophores have been synthesized and their comparative fluorescence has been studied in different organic solvents and aqueous solutions of inorganic ions. Out of these, two highly sensitive fluorophores have been used to label phosphoramidites and oligodeoxyribonucleotides. The fluorescently labelled amidites and oligodeoxyribonucleotides showed good fluorescence signals.

The study was supported by the grants from the DST, New Delhi. We thank Dr. K. C. Gupta, Deputy Director, IGIB, Delhi for providing facilities for fluorescence measurements.

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