Abstract
A set of novel chiral pyrrolidine-based nucleotide mimics, in which nucleobase, hydroxyl group and phosphonic acid residue were attached to different carbon atoms of the pyrrolidine ring, was synthesized. These monomers were used for the synthesis of the corresponding oligomers, and their physico-chemical properties were evaluated.
The authors thank Russian Foundation of Basic Research for financial support.
Notes
a Examination is currently in progress.