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Original Articles

An Expeditious Synthesis of Benzoxazine-2-Thione c-Nucleosides Via Cu(OTf)2-Mediated Dehydrazinative β-Glycosylation

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Pages 1227-1237 | Received 08 Jul 2008, Accepted 20 Aug 2008, Published online: 26 Nov 2008
 

Abstract

A novel expeditious synthetic protocol for 1,3-benzoxazine-2-thione C-nucleosides via Cu(OTf)2-mediated dehydrazinative β-glycosylation of 4-hydrazino-2H-benz[e]-1,3-oxazine-2-thiones with unprotected D-ribose is reported.

We sincerely thank the Sophisticated Analytical Instrument Facility (SAIF), Punjab University, Chandigarh, for providing microanalyses and spectra.

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