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Nucleosides and Nucleotides Volume 13, 1994 - Issue 1-3
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Original Articles

Selective Synthesis of 6-Ribo- (and Xylo) Pyrano and Furano Aminopyrimidines1. Anticancer and Anti-AIDS Activities

M. Nogueras Dpto. Química Orgánica, Facultad de Ciencias Experimentales, Universidad de Jaén, 23071, JAEN, SPAIN
,
J. Cobo Dpto. Química Orgánica, Facultad de Ciencias Experimentales, Universidad de Jaén, 23071, JAEN, SPAIN
,
M. L. Quijano Dpto. Química Orgánica, Facultad de Ciencias Experimentales, Universidad de Jaén, 23071, JAEN, SPAIN
,
M. Melguizo Dpto. Química Orgánica, Facultad de Ciencias Experimentales, Universidad de Jaén, 23071, JAEN, SPAIN
,
A. Sánchez Dpto. Química Orgánica, Facultad de Ciencias Experimentales, Universidad de Jaén, 23071, JAEN, SPAIN
&
M. Melgarejo Dpto. Química Orgánica, Facultad de Farmacia, Universidad de Granada, 18071, GRANADA, SPAIN
Pages 447-457 | Received 24 May 1993, Accepted 12 Oct 1993, Published online: 23 Sep 2006
 
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Abstract

The synthesis and the anticancer and anti-AIDS activity of some 6-ribo (and xylo) pyrano and furano aminopyrimidines have been carried out. Isomerization to ribopyranose has been observed when per-O-acyl ribofuranoses were deprotected under basic medium.

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Related Research Data

Preparation and application of triphenyl(propyl-3-hydrogen sulfate)phosphonium bromide as new efficient ionic liquid catalyst for synthesis of 5-arylidene barbituric acids and pyrano[2,3-d]pyrimidine derivatives
Source: Springer Science and Business Media LLC
One-pot pseudo three-component condensation reaction of arylglyoxal monohydrates with 1-ethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione for the synthesis of new pyrano[2,3-d:6,5-d’]dipyrimidines as HIV integrase inhibitor-like frameworks using two different environmentally benign catalytic systems
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