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ACKNOWLEDGEMENT
An earlier version of this article was presented as The John P. McGovern Award Lectureship of the American Osler Society at the Society's Annual Meeting on May 2, 2006, in Halifax, Nova Scotia. That article was published by the Society as a monograph. An edited and significantly expanded version is presented here with the kind permission of the American Osler Society. I would like to acknowledge grant support from the Charles A. Dana Foundation (Mending the Brain, Minding Our Ethics II) and the Buster Foundation (Neuroethics and Disorders of Consciousness) as well as the insights of Nicholas D. Schiff, Elizabeth G. Nilson, Cathleen A. Acres, and Amy B. Ehrlich and very constructive comments of the journal's peer reviewers.