Acknowledgment
This research was supported by NIDA Grant DA011015, DA012845, DA021913 and DA021905. The authors would also like to acknowledge the thoughtful contributions of Joseph Sakai, MD. Disclosure: Marilyn Coors is married to the Chairman of MillerCoors; the company has not contributed any funds nor had any influence on the study. The other authors have no financial relationships that relate to the topic of this research.