Short-term effects of fine particulate air pollution on hospital admissions for hypertension: A time-stratified case-crossover study in Taipei

ABSTRACT

This study was undertaken to determine whether there was a correlation between fine particle (PM_2.5) levels and hospital admissions for hypertension in Taipei, Taiwan. Hospital admissions for hypertension and ambient air pollution data for Taipei were obtained for the period from 2009 to 2013. The relative risk of hospital admissions was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. For the single pollutant model (without adjustment for other pollutants), the risk of hospital admissions for hypertension was estimated to increase by 12% on warm days (>23°C) and 2% on cool days (<23°C), respectively. There was no indication of an association between levels of PM_2.5 and risk of hospital admissions for hypertension. In two-pollutant model, PM_2.5 remained nonsignificant after inclusion of any of the other air pollutants (SO₂, NO₂, CO, or O₃) both on warm and cool days, but a numerically greater response was seen on warm days. Data thus indicate that in Taipei, hospital admissions for hypertension occur as a consequence of factors not related to ambient air exposure.

Acknowledgments

This study is based in part on data from the National Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health and managed by National Health Research Institutes. The interpretation and conclusions contained herein do not represent those of Bureau of National Health Insurance, Department of Health, or National Health Research Institutes.

Funding

This study was supported by a grant from Wang Jhan-Yang Trust Fund (WJY 2016-HR-01) and National Health Research Institutes, Taiwan (EM-105-PP-08).