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Abstract
In vitro toxicity of n‐hexane and 2,5‐hexanedione using isolated perfused rabbit heart is reported. The hearts were perfused using Langendorf's procedure and modified Anderson's coronary perfusion apparatus. The force of cardiac contraction was significantly reduced following 1 h perfusion with 9.6 mg/l concentration of n‐hexane and with 0.35% v/v concentration of 2,5‐hexanedione.