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Abstract
Rabbits were exposed (2h/d) to atmospheres consisting of 0.5 mglrn 3 (0.3 μm) H 2 SO A plus NO 2 at either 0.3 (low) or 1 ppm (high). Animals were sacrificed 24 h after 2, 6, or 13 exposures, and cells were recovered from the lungs by bronchopulmonary lavage. Exposure to high NO 2 with acid resulted in an increase in neutrophils at all time points and an increase in phagocytic capacity of macrophages after two or six exposures. On the other hand, exposure to the low NO 2 with acid resulted in depressed phagocytic capacity and mobility. The results were compared with those for NO 2 or H 2 SO 4 given alone.
