Multiplex assay for multiomics advances in personalized-precision medicine

ABSTRACT

Building the future of precision medicine is the main focus in cancer domain. Clinical trials are moving toward an array of studies that are more adapted to precision medicine. In this domain, there is an enhanced need for biomarkers, monitoring devices, and data-analysis methods. Omics profiling using whole genome, epigenome, transcriptome, proteome, and metabolome can offer detailed information of the human body in an integrative manner. Omes profiles reflect more accurately real-time physiological status.

Personalized omics analyses both disease as a whole and the main disease processes, for a better understanding of the individualized health. Through this, multi-omic approaches for health monitoring, preventative medicine, and personalized treatment can be targeted simultaneously and can lead clinicians to have a comprehensive view on the diseasome.

KEYWORDS:

• Precision medicine
• omics technology
• personalized medicine
• target therapy

Acknowledgments

All authors had equal contribution in preparing this paper.

Additional information

Funding

The work has been partially supported by the Executive Agency for Higher Education, Research, Development and Innovation Funding, under grant PN-III-P1.1-PD-2016-2093, contract no.121/2018, Bucharest, Romania.