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Articles

Factors associated with adherence to antiretroviral therapy among HIV + Patients in Guangxi, China

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Pages 26-47 | Received 26 Nov 2017, Accepted 12 Feb 2019, Published online: 25 Mar 2019
 

Abstract

This study employed logistic regression to examine the factors that predict medication adherence among a total of 2,146 HIV-infected individuals who were receiving antiretroviral therapy (ART) in Guangxi, China. Of these participants, 1,388 patients (64.7%) did not miss any medication dose. Medication-specific social support (OR = 1.50, 95% CI: 1.05–2.13), no/less experience of influential side effects (OR = 1.38, 95% CI: 1.05–1.81), and direct coping (OR = 1.11, 95% CI: 1.01–1.22) are significant predictors of never missing doses. However, longer duration of receiving ART (OR = 1.60, 95% CI: 1.00–2.57), ever use of synthetic drugs (OR = 2.70, 95% CI: 1.58–4.61), and actively social support seeking (OR = .95, 95% CI: .90–.99) are significant predictors of ever missing adherence. HIV treatment and care in Guangxi should address potential treatment fatigue, offer medication-specific social support, and help patients to prevent, reduce, or manage side effects of treatment. Continuing research is greatly needed on the influence of coping strategies on medication adherence.

Additional information

Funding

Dr. Xiaoming Li was supported by NIAAA grant [R01AA018090] and NICHD grant [R01HD074221]. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Health.

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