Article title: SUMOylation of p53 mediates interferon activities
Authors: Laura Marcos-Villar, José Pérez-Girón, Jessica Vilas, Atenea Soto, Carlos de la Cruz-Hererra, Valerie Lang, Manuel Collado, Anxo Vidal, Manuel Rodriguez, Cesar Muñoz-Fontela & Carmen Rivas
Journal: Cell Cycle
Bibliometrics: Volume 12, Issue 17, pages 2809–2816
DOI: 10.4161/cc.25868
The authors of the above article request the publication of corrections to Figure1D and 2B. Inputs shown in panels 1D and 2B did not correspond with the Histidine-tagged purified samples in the above article. The corrected Figures are shown below. This error does not affect original results or conclusions. The authors apologize and accept responsibility for not detecting these errors prior to publication.
Figure 1. IFN-α treatment of HEK-293 cells induces p53 SUMOylation. (A) Stimulation of p53 SUMOylation after treatment for 16 h with different concentrations of IFN-α. (B) Stimulation of p53 SUMOylation after treatment with 500 U/ml of IFN-α for different periods of time.
Figure 2. VSV infection induces the conjugation of SUMO1 and SUMO2/3 to the lysine residue 386 in p53. (A) p53 SUMOylation after 4h of VSV infection. (B) Timecourse experiment showing p53 SUMOylation during VSV infection. (C) Colocalization of GFP-p53 and SUMO2 or SUMO1 in VSV infected MCF7 cells (left panel) and HEK-293 cells (right panel), respectively. (D) VSV infection induces the SUMOylation of p53-WT, but not of p53-K386R mutant.
