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Molecular Crystals and Liquid Crystals Volume 445, 2006 - Issue 1
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Original Articles

Pulsed-Laser Induced Fragmentation and Dissociation of DNA Immobilized on Gold Nanoparticles

Yasuro Niidome Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, JapanCorrespondence[email protected]
,
Takuro Niidome Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, Japan
,
Sunao Yamada Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, Japan
,
Yukichi Horiguchi Department of Materials Physics and Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, Japan
,
Hironobu Takahashi Department of Materials Physics and Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, Japan
&
Kahako Nakashima Department of Applied Chemistry, Faculty of Engineering, Nagasaki University, Nagasaki, Japan
Pages 201/[491]-206/[496] | Published online: 23 Aug 2006
 
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ABSTRACT

Plasmid DNA was immobilized on positively-charged gold nanoparticles (GNPs). Pulsed-laser irradiation induced fragmentation and dissociation of DNA from the GNP-DNA complexes. Dissociation of DNA without degradation was achieved when 80- mJ/pulse of laser light irradiated the GNP-DNA complexes.

Acknowledgments

This work was supported in part by the Industrial Technology Research Grant Program in ′04 from the New Energy and Industrial Technology Development Organization (NEDO).

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