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Molecular Crystals and Liquid Crystals Volume 640, 2016 - Issue 1: 10th International Conference on Electronic Processes in Organic and Inorganic Materials (ICEPOM-10)
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Original Articles

L-ascorbic acid release from polymeric matrixes based on blends of chitosan, collagen and hyaluronic acid

B. KaczmarekNicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, Torun, Poland
,
A. SionkowskaNicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, Torun, PolandCorrespondence[email protected]
&
E. MarkiewiczNicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, Torun, Poland
Pages 46-53 | Published online: 14 Dec 2016
 
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ABSTRACT

3D porous composites based on blends of chitosan, collagen and hyaluronic acid were obtained. L-ascorbic acid was incorporated into the composites. The structure of composites was studied by IR spectroscopy and SEM. Moreover, mechanical properties, porosity and density of the blends were studied. The release of L-ascorbic acid from biopolymeric matrixes was studied by UV-Vis spectroscopy.

 The results showed that biopolymeric matrixes based on the blends of chitosan, collagen and hyaluronic acid can be used as 3D systems for L-ascorbic acid delivery. The addition of hyaluronic acid to chitosan/collagen blends leads to the decrease of amount of released agent.

Acknowledgment

Financial support from the National Science Centre (NCN, Poland) Grant No UMO-2013/11/B/ST8/04444 is gratefully acknowledged.

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