Design and structural characterization of 2-methyl 8-hydroxyl quinolinilium 5-chloro salicylate salt

Abstract

The enhanced physico chemical properties of 2-methyl 8-hydroxy quinolone was observed by the modified 2-methyl 8-hydroxy quinolinium 5-chloro salicylate crystal structure which were grown by slow evaporation method. The crystal structure was confirmed by single X-ray diffraction analysis. Crystal structure was stabilized through halogen bond interaction in the title crystal. The 3D Hirshfeld surfaces and the associated 2D fingerprint plots were investigated for intermolecular hydrogen bonding interactions. FTIR and FT-Raman spectral studies were characterized to reveal the presence of functional groups in the grown crystal. The proton and carbon chemical shift of the title compound were observed by ¹H and ¹³C NMR analysis. Excited energy of the title compound was observed using UV-Visible spectral analysis. The fluorescence solid and solvent spectrum revealed that the green emission was observed in the grown crystal. The melting behavior and stability of the title compound was performed by TGA-DSC analysis. The ability to show the pharmacological behavior of the title crystal was analyzed by anti-oxidant, anti-microbial and anti-cancer studies.

Keywords:

• 2-methyl 8-hydroxy quinolone
• 5-chloro salicylic acid
• salt formation
• hydrogen bond
• Hirshfeld analysis
• green emission property
• anti-cancer study

Acknowledgments

The authors are thankful to the management, Sri Sarada College for Women (Autonomous), Salem-636 016 for providing the facilities to carry out this research work.

Disclosure statement

The authors declare no competing financial interest.