Facile and Cost-Effective Development of Silver based Cellulosic Wound Dressing using Electrospraying Process

ABSTRACT

Silver-based wound dressings are deployed for various types of wounds due to its broad antimicrobial activity. Most of the wound dressings are prepared by exhaustion or doping process, which requires excess quality of silver to be used and also leads to burst release. Electrospraying process provides an excellent opportunity to topically apply silver on cationic cellulosic substrates. The cationization of cellulose ensures better bonding of silver nanoparticles thereby ensuring durability for long periods. The developed wound dressing exhibited excellent antimicrobial activity against E. Coli and S. Aureus.

摘要

银基伤口敷料由于其广泛的抗菌活性，被用于各种类型的伤口. 大多数伤口敷料是通过耗尽或掺杂工艺制备的，这需要使用过多质量的棉条，也会导致破裂释放. 电喷雾过程提供了一个极好的机会，局部应用银阳离子纤维素基板. 纤维素的阳离子化确保了银纳米粒子更好的结合，从而确保了长期的耐久性. 研制的创面敷料对大肠杆菌具有良好的抗菌活性. 大肠杆菌和E.Coli 和S.Aureus斯.

KEYWORDS:

• Antibacterial wound dressing
• cationisation
• cellulose
• electrospraying
• silver
• nonwoven
• wet laid

关键词:

• 抗菌敷料
• 阳离子化
• 纤维素
• 电喷雾
• 银色
• 无纺布
• 湿铺.

Acknowledgments

The authors have not received any financial support from any funding sources for this work.