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Original Articles

Free Fatty Acids of Newborns from Women with Gestational Diabetes Mellitus

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Pages 190-194 | Received 04 Nov 2016, Accepted 15 Nov 2016, Published online: 07 Feb 2017
 

ABSTRACT

Introduction: Fetal macrosomia in gestational diabetes mellitus is contributed to by compensatory fetal mechanisms responding to alterations in maternal metabolism. Objectives: To compare FFA and blood glucose concentrations of newborns derived from healthy and hyperglycemic mothers. Methods: Prospective study included two equal groups of term newborns (50) from GDM and healthy mothers. Blood was derived from umbilical and cubital vein of mothers immediately after birth. Results: The mean FFA concentration of mothers did not differ whereas in infants of GDM mothers FFA were significantly lower. A significant correlation was found between FFA levels of healthy mothers and their newborns (p < 0.05). No such correlation was found in GDM group (p > 0.05). A significant correlation was found between mother's and newborn's glycemia (p < 0.05) in both groups. Conclusion: Suppression of FFA acids in newborn blood of mothers with GDM may represent the lipogenic and antilipolytic activity of the fetus.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

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